Unfortunately, this arrival of Europeans caused great tragedies for the Native Americans. Native Americans did not have the immune system that the Europeans had developed being around domesticated animals and the diseases that came with them. This, as well as starvation and probably lack of defense caused sometimes up to 90% of the native population to die. The massacre of all of these Native Americans is one of the worst tragedies for humanity to date.
The loss of so many lives caused a labor shortage and thus the native's that were killed were quickly replaced with more immigrant newcomers as colonizing Europeans and enslaved Africans. Along with a change in people came a Europeans change in diet for the Americas (with the arrival of pigs and cattle and such) as well as the Eastern Hemisphere (whom adopted some American foods like corn and potatoes).
An Atlantic Network was created with the trade of slaves, food, and other resources, though it was the Western Hemisphere or more so the Europeans that conquered it who dominated this "Atlantic World" and globalization. Two "Old World's" were quickly becoming a globalized "New World".
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